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Selected Recent Publications

Cancer treatment alters mutant selection in normal esophagus

Joanna C. Fowler, Giuseppina Arbore, Roshan K. Sood, Irina Abnizova, Luca Albarello, Oliver Pickering, Kasumi Murai, Ujjwal Banerjee, Salomé Brunon, Swee Hoe Ong, Andrea Cossu, Ugo Elmore, Francesco Puccetti, David Fernandez-Antoran, Giovanni Tonon, Paolo Dellabona, Riccardo Rosati, Samuel Luke Hill, Tim Underwood, Benjamin A. Hall*, David Shorthouse & Philip H. Jones. Nature Genetics 2026

Large-scale computational modelling of the M1 and M2 synovial macrophages in rheumatoid arthritis

Naouel Zerrouk, Rachel Alcraft, Benjamin A Hall, Franck Augé, Anna Niarakis. npj Systems Biology and Applications 2024 

KCNQ potassium channels modulate WNT activity in gastro-oesophageal adenocarcinomas

David Shorthouse, Lizhe Zhuang, Eric P Rahrmann, Cassandra Kosmidou, Katherine Wickham Rahrmann, Michael Hall, Benedict Greenwood, Ginny Devonshire, Richard J Gilbertson, Rebecca C. Fitzgerald, Benjamin A Hall. Life Sciences Alliance 2023

SMAD4 and KCNQ3 alterations are associated with lymph node metastases in oesophageal adenocarcinoma

Kieran Foley, David Shorthouse, Eric Rahrmann, L Zhuang, G Devonshire, RJ Gilbertson; OCCAMS consortium; Rebecca C Fitzgerald, Benjamin A Hall. Biochim Biophys Acta Mol Basis Dis. 2023 

Mutations observed in somatic evolution reveal underlying gene mechanisms 

Michael W. J. Hall, David Shorthouse, Rachel Alcraft, Philip H. Jones & Benjamin A. Hall. Communications Biology 2023

Selected Preprints

Dynamics of the B-Cell gene regulatory network in differentiation determine evolutionary trajectories of childhood leukaemogenesis

Matthieu Bouguéon, Jason Wray, Tariq Enver, Benjamin A Hall, bioRxiv

Validating folding energy estimates as a method for variant interpretation

Clementine Elwes, Rachel Alcraft, Harris Lister, Paul Smith, David Shorthouse, Benjamin A Hall, bioRxiv

Somatic mutant selection is altered by prior NOTCH1 mutation in aging esophageal epithelium

Charlotte King, Joanna C Fowler, Emilie Abby, Kasumi Murai, Roshan K Sood, Irina Abnizova, Salomé Brunon, Swee Hoe Ong, Faye Lynch Williams, Michael W J Hall, Benjamin A Hall, Philip H Jones, bioRxiv

Reviews and book chapters

Data integration in logic-based models of biological mechanisms.

Benjamin A Hall and Anna Niaraki. Current Opinion In Systems Biology (2021)

Cellular survival over genomic perfection.

S Nik-Zainal, Benjamin A Hall, Science (2019)

Bacterial Chemotaxis

Kathryn A Scott, Elizabeth E Jefferys, Benjamin A Hall, Mark AJ Roberts, Judith P Armitage. Bacterial Regulatory Networks (2012)

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